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RADAR+ Interview with prof. dr. Terwindt
Two million Dutch people suffer from migraine, women twice as often as men. Acute medication is less effective in women. Prof. dr. Terwindt from the LUMC: ‘Women with migraine have the right to better answers’. Read the full article here (in Dutch).
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Gender specific practice in neurology starts at the GP
Prof. dr. Terwindt was interviewed by DOQ. Read the full article here (in Dutch).
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Less benefits, more side effects
Women benefit less from triptans – migraine drugs – than men. In addition, women more often suffer from side effects. This was demonstrated in a study by the LUMC and Erasmus MC. Read more in this interview in Leidsch Dagblad (in Dutch).
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Can migraine patients benefit from the oral contraceptive pill?
Each month WOMEN Inc. asks a researcher 5 questions. This month: Antoinette Maassen van den Brink, farmacologist and researcher from the Erasmus MC, about her research on the relationship between hormones and migraine. Read the full article here (in Dutch).
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Women respond differently to treatment of migraine with triptans than men
Headache researchers from the Leiden University Medical Center (LUMC) and the Erasmus Medical Center (Erasmus MC) concluded that women more often experience headache recurrences after the intake op triptans and report more side effects. The results have been published in the journal Neurology. See for the full article the LUMC website.
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News article in Nature: Closing the gender gap in migraine research
“Terwindt notes that many general practitioners remain unaware of the aura-associated risk of stroke, and prescribe oral contraception as a stabilizing treatment for migraine without full knowledge of the risks or clear evidence of the benefits. “It’s just trial and error,” she says. She and Maassen van den Brink have launched a study to establish more firmly whether hormonal treatment helps manage migraine.” Read the full article here.
Publicaties
van der Arend, BWH, van Casteren, DS, Verhagen, IE et al. Continuous combined oral contraceptive use versus vitamin E in the treatment of menstrual migraine: rationale and protocol of a randomized controlled trial (WHAT!). Trials 25, 123 (2024). PubMed.
Verhagen, IE, de Vries Lentsch, S, van der Arend, BWH, le Cessie, S, MaassenVanDenBrink, A, Terwindt, GM. Both perimenstrual and nonperimenstrual migraine days respond to anti-calcitonin gene-related peptide (receptor) antibodies. Eur J Neurol. 2023; 30: 2117- 2121. PubMed.
Verhagen IE, van der Arend BW, van Casteren DS, et al. Migraine with and without aura in relation to the menstrual cycle and other hormonal milestones: A prospective cohort study. Cephalalgia. 2023;43(6). PubMed.
Verhagen IE, van der Arend BWH, van Casteren DS, le Cessie S, MaassenVanDenBrink A, Terwindt GM. Sex differences in migraine attack characteristics: A longitudinal E-diary study. Headache. 2023; 63: 333-341. PubMed.
Verhagen IE, Spaink HA, van der Arend BW, van Casteren DS, MaassenVanDenBrink A, Terwindt GM. Validation of diagnostic ICHD-3 criteria for menstrual migraine. Cephalalgia. 2022 Oct; 42(11-12): 1184-1193. PubMed.
Verhagen, I.E., Brandt, R.B., Kruitbosch, C.M.A., MaassenVanDenBrink A, Fronczek R, Terwindt GM. Clinical symptoms of androgen deficiency in men with migraine or cluster headache: a cross-sectional cohort study. Journal of Headache and Pain 22, 125 (2021). PubMed.
van Casteren DS, Verhagen IE, BWH van der Arend, EW van Zwet, MaassenVanDenBrink A, Terwindt GM. Comparing perimenstrual and nonperimenstrual migraine attacks using an E-diary. Neurology. 2021 Sep. PubMed.
van Casteren DS, Verhagen IE, Onderwater GL, MaassenVanDenBrink A, Terwindt GM. Sex differences in prevalence of migraine trigger factors: A cross-sectional study. Cephalalgia. 2021 May; 41(6):643-648. PubMed.
van Casteren DS, Kurth T, Danser AHJ, Terwindt GM, MaassenVanDenBrink A. Sex Differences in Response to Triptans: A Systematic Review and Meta-analysis. Neurology. 2021 Jan 26; 96(4):162-170. PubMed.
van Casteren DS, Verhagen IE, de Boer I, de Vries Lentsch S, Fronczek R, van Zwet EW, MaassenVanDenBrink A, Terwindt GM. E-diary use in clinical headache practice: A prospective observational study. Cephalalgia. 2021 Oct; 41(11-12): 1161-1171. PubMed.
van Casteren DS, van Willigenburg FAC, MaassenVanDenBrink A, Terwindt GM. Jealousy in women with migraine: a cross-sectional case-control study. The Journal of Headache and Pain. May 2020. PubMed.
van Casteren DS, MaassenVanDenBrink A, Terwindt GM. Migraine and other headache disorders in pregnancy. Handbook of Clinical Neurology. 2020. PubMed.